Two years sit on two opened pages
The Orapred ODT highlights line is a US label field: Initial U.S. Approval: 1955. That field sits on the DailyMed page for prednisolone sodium phosphate orally disintegrating tablets. It is the year that label prints. The opened label does not attach a chemist, a ward date, or a 5 mg chip to that year.
DrugBank DB00860 prints a different pair. The card says First approval Canada, 1967 · United States, 1974. The database and the label were both open on 24 October 2026. They still name different years. This desk leaves the disagreement on the page. A reader who needs one year for a citation should quote the page they opened, and should say which page it was.
The 1950 prize names adrenal hormones
The Nobel Prize in Physiology or Medicine 1950 was awarded jointly to Edward Calvin Kendall, Tadeus Reichstein and Philip Showalter Hench "for their discoveries relating to the hormones of the adrenal cortex, their structure and biological effects". That sentence is the prize citation on the Nobel Prize site. It names Kendall, Reichstein, and Hench. It does not say prednisolone. The prize year is earlier than 1955 on the ODT label and earlier than 1974 on the DrugBank card.
The opened label, the prize page, and the DrugBank card stop at the year, the prize citation, and the chemical name. A laboratory scene that is not on those pages stays off this one.
What the solution label calls the molecule
The TruPharma oral solution label says the product contains prednisolone which is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. The chemical name for Prednisolone is Pregna-1,4 -diene -3, 20 - dione, 11, 17, 21- trihydroxy-,(11β). Its molecular weight is 360.45.
DrugBank lists other names on the same card: delta-dehydrocortisol · delta-dehydrohydrocortisone · delta-hydrocortisone · delta(1)-Dehydrocortisol · delta(1)-Hydrocortisone. Those aliases belong to this record. They are a second way to spell the same substance, and they still do not settle the approval year.
1955 on a prednisone story is the other drug
A public sentence about prednisone that uses 1955 is about prednisone. It is not the Orapred ODT approval field, even when the same year appears in both places. Keep the steroid names separate.
Labeled uses, including the short-term and infection limits, are on the prednisolone uses note. How a course comes down is on prednisolone tapering. The medicine page is prednisolone. The ODT text is the Orapred ODT label. The prize page is the 1950 Nobel summary.